Hamilton scored 240 points overall and placed 4th, 16 points behind the drivers' champion Sebastian Vettel while Button was classified 5th with 214 points. The team finished second in the season, with 454 points in the Constructors Championship, behind the constructors' champion Red Bull Racing (498 points). The car was competitive overall, with 1 pole position set (Hamilton at the 2010 Canadian Grand Prix), 16 podium finishes (Button 7 Hamilton 9), 6 fastest laps set (Button 1 Hamilton 5) and 5 race victories (Button 2 Hamilton 3). The car was driven by reigning world champion Jenson Button, who switched that year from Brawn GP, and 2008 World Champion Lewis Hamilton. It utilizes Bridgestone tires, which was also the final year Bridgestone supplied tires to Formula one until Pirelli took over. Mercedes was also the main engine supplier for the team until it was replaced by Honda in 2015. The MP4-25 uses a 2.4-liter Mercedes V8 engine, which was the standard engine format for all cars until 2013. The car was however cleared inspections prior to the season opener at the Bahrain Grand Prix. It was mildly controversial, with the Red Bull Racing team complaining to the FIA about the legality. Another term for the system is switchable rear wing (SRW). Known internally as the RW80 it is widely called the 'F-Duct' system either due to the shape of the air intake or the fact that it is beside the F of the Vodafone logo. The effect is controlled by the driver covering up a small hole in the cockpit with his left leg. Changes in the pressure in the duct, in combination with small slots on the rear wing, causes the wing to enter a stalled state at high speed, reducing aerodynamic drag, and allowing the car as much as an extra 6 mph (9.7 km/h) on straights. The design uses a small 'snorkel' air scoop mounted in front of the driver that channels air through a duct in the cockpit and towards the rear of the car. The chief designer of the car was Paddy Lowe, who was formerly the technical executive director in the Mercedes-AMG Petronas Formula One Team and Chief Technical Officer of ROKiT Williams Racing.

The McLaren MP4-25 was officially unveiled at title sponsor Vodafone's headquarters in Newbury, Berkshire, United Kingdom on 29 January 2010.

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